Publications

Hentemann et al. “Pharmacological profile and anti-tumor properties of FHD-286, a novel BAF inhibitor for the treatment of transcription factor-driven cancers” AACR, April 2022

Sandoval et al. “Modulation of SPI1 transcriptional program contributes to the preclinical anti-tumor activity of SMARCA4/SMARCA2 ATPase inhibitors in AML” AACR, April 2022

Centore et al. “Discovery of novel BAF inhibitors for the treatment of transcription factor-driven cancers” AACR, April 2021

Centore, Sandoval, Mendes Soares, Kadoch and Chan. “Mammalian SWI/SNF Chromatin Remodeling Complexes: Emerging Mechanisms and Therapeutic Strategies” TIGS 1709 August 29, 2020

Michel et al. “A non-canonical SWI/SNF complex is a synthetic lethal target in cancers driven by BAF complex perturbation” Nat. Cell Biol. 2018 Dec; 20(12): 1410–1420

Kadoch & Crabtree. “Mammalian SWI/SNF chromatin remodeling complexes and cancer: Mechanistic insights gained from human genomics” Science Advances 12 Jun 2015: Vol. 1, no. 5, e1500447

Hodges, Kirkland, and Crabtree. “The Many Roles of BAF (mSWI/SNF) and PBAF Complexes in Cancer” Advance July 13, 2016

Valencia and Kadoch. “Chromatin regulatory mechanisms and therapeutic opportunities in cancer” Nat Cell Biol. 2019 Feb; 21(2): 152–161

Sandoval et al. “Binding of TMPRSS2-ERG to BAF Chromatin Remodeling Complexes Mediates Prostate Oncogenesis” 2018, Molecular Cell 71, 554–566, August 16, 2018